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Dr Mark Kennedy - Private Internal Medicine Specialist

Private Service

Peptic Ulcer Disease

Patient information:
Peptic ulcers are sores or eroded areas that form in the lining of the upper digestive tract. They usually occur in the oesophagus (oesophageal ulcer), stomach (gastric ulcer) or in the duodenum (duodenal ulcer) which is the first part of the small intestine.
People with peptic ulcers can have a wide variety of symptoms and signs. At times they can be completely symptom-free or, much less commonly, can develop potentially life-threatening complications such as bleeding. Signs and symptoms of ulcers include:
  • pain / burning or discomfort (usually in the upper abdomen)
  • bloating
  • an early sense of fullness with eating
  • lack of appetite
  • nausea
  • vomiting
  • bleeding, which is made apparent by blood in the stool, either in noticeable or microscopic amounts (very brisk bleeding will result in melaena with black and tarry stools that smell bad).
Smoking, alcohol, anti-inflammatory medication and aspirin increase the risk of developing ulcers. Psychological stress and dietary factors (once thought to be the cause of ulcers) do not appear to have a major role in their development.
Helicobacter pylori, a bacteria that is frequently found in the stomach is a major cause of stomach ulcers.  If this is found when you have a gastric or duodenal ulcer, you will be given a course of antibiotics.
The diagnosis is made by the history, examination and sometimes blood tests.  You may be asked to have a gastroscopy (see above) to clarify the diagnosis and aid with treatment.
Treatment consists of medication to reduce the amount of acid in the stomach which aids in the healing of ulcers and avoidance of any factor that may have caused the ulcers in the first place.

This page was last updated at 2:04PM on October 8, 2019.